Defining a clinical question in terms of the specific patient problem aids the searcher in finding clinically relevant evidence in the literature. The PICO Model is a format to help define your question.
The P.I.C.O. Model for Clinical Questions
Patient, Population, or Problem
How would I describe a group of patients similar to mine?
Intervention, Prognostic Factor, or Exposure
Which main intervention, prognostic factor, or exposure am I considering?
Comparison or Intervention (if appropriate)
What is the main alternative to compare with the intervention?
Outcome you would like to measure or achieve
What can I hope to accomplish, measure, improve, or affect?